DEPARTAMENTO DE FÍSICA

Biophysics - EB3

Ano letivo: 2014-2015

Specification sheet

Specific details

course code | cycle os studies | academic semester | credits ECTS | teaching language |

1003155 | 1 | 1 | 6 | pt,en |

Learning goals

Biophysics, interdisciplinary science, uses the laws of physics and mathematical methods to explain biological phenomena. The development of methods to analyse and measure physiologic parameters is one of its best known applications. There are several medical areas where physics methods are obvious such cardiology, ophthalmology, orthopaedics, imaging, nuclear medicine, etc.

The goal is to give a general view of Biophysics applications in health sciences, covering different subjects, such as transport mechanisms, bioelectricity, solid state, fluids, radiation and thermodynamics. Special attention will be paid on:

-molecular transport across cellular membranes

-distribution of dipoles and its relation to signal acquisition and clinical interpretation

-physical properties of biological materials and their relation to structure of matter

-fluids behaviour and its relation to pathological situations

-harmful consequences of radiation and their effects, dose limits and radioprotection.

The goal is to give a general view of Biophysics applications in health sciences, covering different subjects, such as transport mechanisms, bioelectricity, solid state, fluids, radiation and thermodynamics. Special attention will be paid on:

-molecular transport across cellular membranes

-distribution of dipoles and its relation to signal acquisition and clinical interpretation

-physical properties of biological materials and their relation to structure of matter

-fluids behaviour and its relation to pathological situations

-harmful consequences of radiation and their effects, dose limits and radioprotection.

Syllabus

1st day - 13:00 ? 20:00 (M Filomena Botelho, M Morgado,M Patrício, F Caramelo, R Bernardes)

Introduction to Biophysics Course

Optical Radiation Protection

Applications with the finite element method

Critical analysis of papers

2nd day - 13:00 ? 20:00 (M Filomena Botelho, F Caramelo, R Bernardes)

Ionizing radiation protection

Biomechanics

Critical analysis of papers

3rd day - 13:00 ? 20:00 (M José Ribeiro, M Filomena Botelho, F Caramelo, R Bernardes)

Interfaces Brain-Computer

Critical analysis of papers

4th day - 13:00 ? 20:00 (A Dourado, R Bernardes, F Caramelo)

Systems and Intelligent Data Analysis in Medicine

Group work: Laboratory component of computer

Elaboration and discussion of report

5th day - 13:00 ? 20:00 (A Paixão, N Ferreira, F Caramelo, M Filomena Botelho)

Structure of matter

laboratory applications

Elaboration and discussion of report

Introduction to Biophysics Course

Optical Radiation Protection

Applications with the finite element method

Critical analysis of papers

2nd day - 13:00 ? 20:00 (M Filomena Botelho, F Caramelo, R Bernardes)

Ionizing radiation protection

Biomechanics

Critical analysis of papers

3rd day - 13:00 ? 20:00 (M José Ribeiro, M Filomena Botelho, F Caramelo, R Bernardes)

Interfaces Brain-Computer

Critical analysis of papers

4th day - 13:00 ? 20:00 (A Dourado, R Bernardes, F Caramelo)

Systems and Intelligent Data Analysis in Medicine

Group work: Laboratory component of computer

Elaboration and discussion of report

5th day - 13:00 ? 20:00 (A Paixão, N Ferreira, F Caramelo, M Filomena Botelho)

Structure of matter

laboratory applications

Elaboration and discussion of report

Prerequisites

Basic knowledge and competences in Biophysics and applied Physics. The course can be held in both Portuguese or English

Generic skills to reach

. Competence in analysis and synthesis;. Competence to solve problems;

. Critical thinking;

. Competence in understanding the language of other specialists;

. Competence in autonomous learning;

. Competence for working in group;

. Competence in working in interdisciplinary teams;

. Planning and managing;

. Research skills;

(by decreasing order of importance)

Teaching hours per semester

seminar | 15 |

tutorial guidance | 20 |

total of teaching hours | 35 |

Assessment

Sseminar or study visit | 30 % |

Exam | 30 % |

Other | análise crítica de artigos científicos: 40 % |

Bibliography of reference

1. ?Intermediate Physics for Medicine and Biology?, 2cd Edition, Russel Hobbie; John Wiley and Sons

2. ?Radiobiology for the Radiologist?, 5th Edition, Eric Hall; Lippincott Williams & Wilkins

3. ?Mathematical Physiology?, James Keener, James Sneyd, Springer

4. ?Éléments de biophysique?, vol I e II, F. Grémy, J. Perrin, Flammarion

5. Biophysics. Searching for principles. William Bialek. Princeton University Press. USA

2. ?Radiobiology for the Radiologist?, 5th Edition, Eric Hall; Lippincott Williams & Wilkins

3. ?Mathematical Physiology?, James Keener, James Sneyd, Springer

4. ?Éléments de biophysique?, vol I e II, F. Grémy, J. Perrin, Flammarion

5. Biophysics. Searching for principles. William Bialek. Princeton University Press. USA

Teaching method

Lectures will be given by a group of leading experts in Biophysics. Beyond that, computational simulations in laboratory environment and small group discussions will allow the PhD students to brainstorm around new research ideas and develop new research projects, always with a face to face interaction with the faculty members. Critical analysis of published research articles will also be performed. Continuous evaluation of the students will be performed during course. There will also be a theoretical evaluation.

Resources used

Acesso a bases de dados bibliográficos, ligação à Internet. Sala de Computadores